Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656843 | 0.94 | CA12 (0.55) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9059137 | 0.87 | CA12 (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8428854 | 0.85 | ALDH1A1 (0.61) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8428853 | 0.83 | MEN1 (0.62) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7442139 | 0.77 | KMT2A (0.66) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3345207 | 0.76 | CA12 (0.68) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL742343 | 0.76 | KMT2A (0.71) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8098635 | 0.75 | ALDH1A1 (0.62) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8488019 | 0.75 | CA12 (0.59) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6094268 | 0.75 | ALDH1A1 (0.62) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465483-B1 | TREATING OR PREVENTING STROKES; CHRONIC INFLAMMATORY DISORDERS SUCH AS BRONCHIAL ASTHMA AND ARTHRITIS; ANTIPROLIFERATIVE EFFECT; ULCERATIVE COLITIS AND CROHN'S DISEASE | BOEHRINGER INGELHEIM GMBH (DE) | 2002-10-15 | — | — | US | disclosed |
| US-6180645-B1 | ANTIEPILEPIC AGENT | BOEHRINGER INGELHEIM GMBH (DE) | 2001-01-30 | — | — | US | disclosed |
| US-5607943-A | CARDIOPROTECTIVE, CEREBROPROTECTIVE, ANTIINFLAMMATORY AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1997-03-04 | — | — | US | disclosed |