SCHEMBL765694

SCHEMBL765694

Cc1ccc2c(Cl)c(C)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
ALDH1A1 P00352 3/20 0.59
HPGD P15428 2/20 0.59
HSD17B10 Q99714 2/20 0.59
KDM4E B2RXH2 1/20 0.59
GAA P10253 1/20 0.59
CYP1A2 P05177 7/20 0.52
CYP2A6 P11509 5/20 0.50
TDP1 Q9NUW8 3/20 0.43
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
BCL2L1 Q07817 1/20 0.36
MCL1 Q07820 1/20 0.36
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
NCK1 P16333 1/20 0.35
BACE1 P56817 1/20 0.35
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14444114 0.83 CYP1A2 (0.50) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL11057827 0.83 POLB (0.46) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL13288386 0.79 NCEH1 (0.49) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL27286459 0.79 CYP1A2 (0.46) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL15976515 0.79 ESR1 (0.58) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL607927 0.78 CYP1A2 (0.71) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL599166 0.77 ALDH1A1 (0.63) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL806512 0.76 CYP19A1 (0.52) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL597341 0.76 CYP1A2 (0.67) LMNAALDH1A1HPGDHSD17B10KDM4E
SCHEMBL2723074 0.76 CYP2A6 (0.52) LMNAALDH1A1HPGDHSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021141507-A1 AROMATIC SULPHONAMIDES DERIVATIVES THAT INHIBITS PDI A3, THEIR SYNTHESIS AND USE Uniwersytet Jagielloński (PL) 2021-07-15 WO disclosed
EP-3453697-A1 COMPOUND HAVING NAPHTHALENE RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2019-03-13 EP disclosed
EP-2302015-B1 OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT JNC CORP (JP) 2016-10-05 EP disclosed
US-8475887-B2 Optically isotropic liquid crystal medium, and optical device JNC CORPORATION (JP) 2013-07-02 US disclosed
US-8475887-B2 Optically isotropic liquid crystal medium, and optical device JNC CORPORATION (JP) 2013-07-02 US disclosed
EP-2098583-B1 Optically isotropic liquid crystal medium and optical device JNC CORP (JP) 2012-03-21 EP disclosed
EP-2302015-A1 OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT Chisso Corporation (JP) 2011-03-30 EP disclosed
US-20110069245-A1 OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT CHISSO PETROCHEMICAL CORPORATION (JP) 2011-03-24 US disclosed
US-20110069245-A1 OPTICALLY ISOTROPIC LIQUID CRYSTALLINE MEDIUM, AND OPTICAL ELEMENT CHISSO PETROCHEMICAL CORPORATION (JP) 2011-03-24 US disclosed
EP-2028252-B1 Liquid crystal compound having chloronaphthalene moiety, liquid crystal composition, and optical device CHISSO CORP (JP) 2010-10-27 EP disclosed
EP-2028252-A1 Liquid crystal compound having chloronaphthalene moiety, liquid crystal composition, and optical device Chisso Corporation (JP) 2009-02-25 EP disclosed
EP-1762605-A1 Naphthalene compound with terminal hydrogen, liquid crystal composition including the compound, and LCD device including the liquid crystal composition Chisso Petrochemial Corporation (JP) 2007-03-14 EP disclosed
US-20070051919-A1 NAPHTHALENE COMPOUND WITH TERMINAL HYDROGEN, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND, AND LCD DEVICE INCLUDING THE LIQUID CRYSTAL COMPOSITION CHISSO PETROCHEMICAL CORPORATION (JP) 2007-03-08 US disclosed
US-20070051919-A1 NAPHTHALENE COMPOUND WITH TERMINAL HYDROGEN, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND, AND LCD DEVICE INCLUDING THE LIQUID CRYSTAL COMPOSITION CHISSO PETROCHEMICAL CORPORATION (JP) 2007-03-08 US disclosed
US-4161607-A Thermally stable, rigid bisphenols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-07-17 US disclosed
US-4107444-A INTERMEDIATES FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-15 US disclosed
US-4096341-A MONOMERS FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-20 US disclosed
US-4085091-A Thermally stable, rigid polyesters from thermally stable, rigid dibasic acids and aromatic dihydroxy compounds E. I. DUPONT DE NEMOURS AND COMPANY (US) 1978-04-18 US disclosed
US-4065432-A Thermally stable, rigid polyesters from aromatic dibasic acids and thermally stable, rigid bisphenols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-27 US disclosed
US-4065431-A Thermally stable, rigid polyesters from aromatic dibasic acids and thermally stable, rigid diols E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070051919-A1 NAPHTHALENE COMPOUND WITH TERMINAL HYDROGEN, LIQUID CRYSTAL COMPOSITION INCLUDING THE COMPOUND, AND LCD DEVICE INCLUDING THE LIQUID CRYSTAL COMPOSITION LEF1, CFD, FOXO1 LMNA 941/4885ALDH1A1 2679/4885HPGD 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.