Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 2/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 13/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | PRKACG | P22612 | 1/20 | 0.31 |
| ▸ | PRKACB | P22694 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7656941 | 0.89 | BDKRB2 (0.35) | BDKRB2CAMK2DPIM1RPS6KB1TSSK1B | |
| Acetic Acid SCHEMBL7657331 | 0.89 | CAMK2D (0.38) | BDKRB2CAMK2DPIM1RPS6KB1TSSK1B | |
| Acetic Acid SCHEMBL7652448 | 0.88 | CAMK2D (0.39) | BDKRB2CAMK2DPIM1RPS6KB1TSSK1B | |
| Acetic Acid SCHEMBL7657858 | 0.88 | TSSK1B (0.37) | BDKRB2CAMK2DPIM1RPS6KB1TSSK1B | |
| Acetic Acid SCHEMBL7658173 | 0.87 | QPCT (0.38) | BDKRB2CAMK2DPIM1RPS6KB1PRKACA | |
| Acetic Acid SCHEMBL7660674 | 0.87 | CAMK2D (0.35) | BDKRB2CAMK2DPIM1RPS6KB1TSSK1B | |
| SCHEMBL7658179 | 0.87 | CAMK2D (0.33) | BDKRB2CAMK2DPIM1RPS6KB1TSSK1B | |
| SCHEMBL7657901 | 0.86 | CHEK1 (0.37) | CAMK2DKDR | |
| SCHEMBL7850355 | 0.86 | CAMK2D (0.44) | CAMK2DPIM1RPS6KB1KDRGSK3B | |
| Acetic Acid SCHEMBL7663715 | 0.86 | BDKRB2 (0.34) | BDKRB2CAMK2DPIM1RPS6KB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458792-B1 | MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. | ASTRAZENECA AB (SE) | 2002-10-01 | — | — | US | disclosed |
| EP-1071683-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999046264-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |