Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7656969

NC[C@H](NS(=O)(=O)c1cccc(C(F)(F)F)c1)C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.62
SLC1A2 P43004 1/20 0.62
NPSR1 Q6W5P4 1/20 0.60
MMP7 P09237 1/20 0.58
ITGB3 P05106 6/20 0.57
ITGAV P06756 6/20 0.57
ITGA2B P08514 6/20 0.57
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
MMP1 P03956 1/20 0.56
MMP2 P08253 1/20 0.56
MMP9 P14780 1/20 0.56
MMP8 P22894 1/20 0.56
MMP13 P45452 1/20 0.56
F2 P00734 5/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
GAA P10253 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
PTPN2 P17706 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7375788 0.96 SLC1A3 (0.66) SLC1A3SLC1A2NPSR1MMP7ITGB3
SCHEMBL7656972 0.83 MMP7 (0.55) SLC1A3SLC1A2NPSR1MMP7ITGB3
SCHEMBL7065939 0.82 NPSR1 (0.68) SLC1A3SLC1A2NPSR1MMP7ITGB3
SCHEMBL4342415 0.81 NPSR1 (0.60) SLC1A3SLC1A2NPSR1MMP7ITGB3
SCHEMBL4342421 0.81 NPSR1 (0.60) SLC1A3SLC1A2NPSR1MMP7ITGB3
SCHEMBL8087637 0.81 L3MBTL1 (0.65) SLC1A3SLC1A2MMP7MMP1MMP2
Trifluoroacetic Acid SCHEMBL7649357 0.80 MMP2 (0.65) SLC1A3SLC1A2MMP7MMP1MMP2
Trifluoroacetic Acid SCHEMBL7653125 0.79 SLC1A3 (0.53) SLC1A3SLC1A2MMP7CA1CA2
SCHEMBL5183965 0.78 MMP7 (0.61) SLC1A3SLC1A2NPSR1MMP7ITGB3
SCHEMBL383079 0.77 MMP2 (0.61) SLC1A3SLC1A2ITGB3ITGA2BMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6335337-B1 ANTICOAGULANTS LABORATOIRE L. LAFON (FR) 2002-01-01 US disclosed