Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.63 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.63 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.63 |
| ▸ | MMP9 | P14780 | 9/20 | 0.59 |
| ▸ | MMP7 | P09237 | 3/20 | 0.59 |
| ▸ | MMP10 | P09238 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 9/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | EEF2K | O00418 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927384 | 0.86 | MMP7 (0.74) | L3MBTL1SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL4927389 | 0.86 | MMP7 (0.74) | L3MBTL1SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL7375788 | 0.84 | SLC1A3 (0.66) | L3MBTL1SLC1A3SLC1A2MMP9MMP7 | |
| SCHEMBL7375346 | 0.84 | SLC1A3 (0.60) | L3MBTL1SLC1A3SLC1A2SLC1A1MMP9 | |
| Trifluoroacetic Acid SCHEMBL7653125 | 0.83 | SLC1A3 (0.53) | L3MBTL1SLC1A3SLC1A2SLC1A1MMP9 | |
| SCHEMBL5191038 | 0.82 | L3MBTL1 (0.80) | L3MBTL1MMP9MMP7MMP2MMP1 | |
| Trifluoroacetic Acid SCHEMBL7649357 | 0.82 | MMP2 (0.65) | SLC1A3SLC1A2SLC1A1MMP9MMP7 | |
| SCHEMBL6500230 | 0.82 | MMP2 (0.61) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL383079 | 0.82 | MMP2 (0.61) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| Trifluoroacetic Acid SCHEMBL7656969 | 0.81 | SLC1A3 (0.62) | L3MBTL1SLC1A3SLC1A2MMP9MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051625-A1 | ASSESSING RISK FOR INTEGRIN ANTAGONIST/AGONIST MEDIATED DISEASES | Du Pont Pharmaceuticals Company (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038014-A1 | ASSESSING RISK FOR INTEGRIN ANTAGONIST/AGONIST MEDIATED DISEASES | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-07-29 | — | — | WO | disclosed |