Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662005 | 0.90 | HTR7 (0.49) | LSSKMT2AKDM4EMEN1TPSAB1 | |
| SCHEMBL7660934 | 0.86 | LSS (0.48) | LSSKMT2AKDM4EMEN1TPSAB1 | |
| SCHEMBL6975859 | 0.79 | LSS (0.71) | LSSALDH1A1HPGD | |
| SCHEMBL7653537 | 0.76 | LSS (0.66) | LSSTPSAB1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7662786 | 0.74 | LSS (0.53) | LSSTPSAB1ALDH1A1PKM | |
| SCHEMBL7682080 | 0.73 | LSS (0.54) | LSSKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL22032750 | 0.73 | MEN1 (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7651857 | 0.72 | LSS (0.50) | LSSTPSAB1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL7650545 | 0.72 | CNR1 (0.64) | LSSKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7651807 | 0.72 | LSS (0.61) | LSSKMT2AKDM4EMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335341-B1 | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 2002-01-01 | — | — | US | disclosed |