Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5755287 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRALDH1A1TP53HIF1A | |
| SCHEMBL26078304 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRALDH1A1TP53HIF1A | |
| SCHEMBL3295702 | 0.91 | TSHR (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7264454 | 0.88 | ATM (0.39) | SMN1; SMN2TSHRALDH1A1ATMNPSR1 | |
| SCHEMBL9434107 | 0.88 | ATM (0.39) | SMN1; SMN2TSHRALDH1A1ATMNPSR1 | |
| SCHEMBL10373574 | 0.85 | ALDH1A1 (0.45) | SMN1; SMN2TSHRALDH1A1TP53HIF1A | |
| SCHEMBL10480992 | 0.85 | ALDH1A1 (0.45) | SMN1; SMN2TSHRALDH1A1TP53HIF1A | |
| SCHEMBL3198964 | 0.85 | TSHR (0.50) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11557485 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRALDH1A1TP53HIF1A | |
| SCHEMBL11589795 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12441687-B2 | Drp1-filamin complex formation inhibitors | Rdiscovery, LLC (US) | 2025-10-14 | — | — | US | disclosed |
| CN-119859377-A | Polyacetal resin composition | 旭化成株式会社 | 2025-04-22 | — | — | CN | disclosed |
| CN-114206441-B | Drp 1-filamin complex formation inhibitors | R发现有限责任公司 | 2024-07-02 | — | — | CN | disclosed |
| US-20220169613-A1 | Drp1-FILAMIN COMPLEX FORMATION INHIBITORS | Rdiscovery, LLC | 2022-06-02 | — | — | US | disclosed |
| EP-3976177-A1 | DRP1-FILAMIN COMPLEX FORMATION INHIBITORS | RDiscovery, LLC (US) | 2022-04-06 | — | — | EP | disclosed |
| CN-114206441-A | Drp 1-inhibitor of filamin complex formation | R发现有限责任公司 | 2022-03-18 | — | — | CN | disclosed |
| WO-2020241638-A1 | Drp1-FILAMIN COMPLEX FORMATION INHIBITORS | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2020-12-03 | — | — | WO | disclosed |
| US-9399019-B2 | Polymorph compositions, methods of making, and uses thereof | EVONIK CORPORATION (US) | 2016-07-26 | — | — | US | disclosed |
| CN-105038011-A | Polyvinyl chloride-polyimide underground pipe special for saline-alkali soil salt elimination and preparation method of polyvinyl chloride-polyimide underground pipe | WEIFANG YOURONG INDUSTRY CO LTD | 2015-11-11 | — | — | CN | disclosed |
| US-8821944-B1 | Polymorph compositions, methods of making, and uses thereof | EVONIK CORPORATION | 2014-09-02 | — | — | US | disclosed |
| EP-0400660-A1 | 1,4-dihydropyridine derivatives | FUJIREBIO INC. (JP) | 1990-12-05 | — | — | EP | disclosed |
| EP-0371492-A2 | Process for the preparation of 1,4-dihydropyridine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| EP-0094159-B1 | DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-14 | — | — | EP | disclosed |
| US-4892875-A | HYPOTENSIVE, RENAL VASODILATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0324626-A1 | 1,4-Dihydropyridine derivatives | Korea Research Institute of Chemical Technology (KR) | 1989-07-19 | — | — | EP | disclosed |
| US-4727066-A | CARDIOVASCULAR DISORDERS | CERMOL S.A. (CH) | 1988-02-23 | — | — | US | disclosed |
| US-4656181-A | CARDIOTONIC AGENTS | CERMOL S.A. (CH) | 1987-04-07 | — | — | US | disclosed |
| US-4558058-A | HYPOTENSIVE AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-12-10 | — | — | US | disclosed |
| US-4532248-A | Administering 1,4-dihydropyridine derivative exhibiting positive inotropic activity | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |
| EP-0094159-A1 | Dihydropyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169613-A1 | Drp1-FILAMIN COMPLEX FORMATION INHIBITORS | FIS1, DNM1L, DNM1 | SMN1; SMN2 2632/4885TSHR 4641/4885ALDH1A1 4345/4885 |
| US-12441687-B2 | Drp1-filamin complex formation inhibitors | FIS1, DNM1L, DNM1 | SMN1; SMN2 2632/4885TSHR 4641/4885ALDH1A1 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.