SCHEMBL7657363

SCHEMBL7657363

CCN(C)C(=S)NCc1ccc(Cl)nc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 1/20 0.44
LMNA P02545 1/20 0.43
ALDH1A1 P00352 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NAMPT P43490 2/20 0.39
HDAC1 Q13547 1/20 0.39
CYP2C9 P11712 1/20 0.39
OXTR P30559 1/20 0.39
AVPR1A P37288 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7665723 0.87 KDM4E (0.47) FAAHKDM4EGAAL3MBTL1MAPT
SCHEMBL7662037 0.80 LMNA (0.43) FAAHKDM4EGAAL3MBTL1MAPT
SCHEMBL7662024 0.76 GAA (0.49) FAAHKDM4EGAAL3MBTL1MAPT
SCHEMBL3663528 0.75 ALDH1A1 (0.41) FAAHKDM4EGAAL3MBTL1MAPT
SCHEMBL888609 0.75 FAAH (0.43) FAAHKDM4EGAAL3MBTL1MAPT
SCHEMBL2801383 0.75 FAAH (0.43) FAAHKDM4EGAAL3MBTL1MAPT
SCHEMBL3668188 0.75 ALDH1A1 (0.41) FAAHKDM4EGAAL3MBTL1MAPT
Potassium Ion SCHEMBL8046032 0.74 CTSL (0.55) FAAHKDM4EGAAL3MBTL1MAPT
SCHEMBL7657370 0.74 ALDH1A1 (0.41) KDM4EGAAL3MBTL1MAPTLMNA
SCHEMBL5012151 0.73 FAAH (0.61) FAAHKDM4EGAAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed