Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322296 | 0.86 | CASP6 (0.38) | CASP6CHRNB2CHRNA4SMN1; SMN2ALDH1A1 | |
| SCHEMBL10512597 | 0.85 | EPHX1 (0.38) | CASP6CHRNB2CHRNA4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9521661 | 0.83 | ALDH1A1 (0.43) | CASP6CHRNB2CHRNA4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9864816 | 0.80 | KCNK3 (0.35) | CASP6CHRNB2CHRNA4SMN1; SMN2ALDH1A1 | |
| SCHEMBL7664002 | 0.79 | FAAH (0.44) | CASP6CHRNB2CHRNA4SMN1; SMN2ALDH1A1 | |
| SCHEMBL7664009 | 0.79 | FAAH (0.44) | CASP6CHRNB2CHRNA4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8070292 | 0.77 | CHRNB2 (0.41) | CASP6CHRNB2CHRNA4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8069181 | 0.77 | MEN1 (0.42) | CASP6CHRNB2CHRNA4SMN1; SMN2ALDH1A1 | |
| SCHEMBL8631374 | 0.75 | MAPK1 (0.39) | CASP6SMN1; SMN2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL8631371 | 0.75 | MAPK1 (0.39) | CASP6SMN1; SMN2ALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407248-B1 | INSECTICIDES, MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |