Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14108207 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2NPC1POLBMAPT | |
| SCHEMBL3044852 | 0.81 | ALDH1A1 (0.56) | LMNASMN1; SMN2HTTNPC1POLB | |
| SCHEMBL4812933 | 0.81 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2HTTNPC1POLB | |
| SCHEMBL31493863 | 0.81 | ABCB11 (0.48) | LMNASMN1; SMN2HTTNPC1POLB | |
| SCHEMBL28731757 | 0.81 | ABCB11 (0.48) | LMNASMN1; SMN2HTTNPC1POLB | |
| SCHEMBL5761877 | 0.77 | TSHR (0.50) | LMNASMN1; SMN2HTTNPC1POLB | |
| Ammonia Solution, Strong SCHEMBL5763481 | 0.76 | TSHR (0.49) | LMNASMN1; SMN2HTTNPC1POLB | |
| SCHEMBL28442399 | 0.75 | KDM4E (0.48) | LMNASMN1; SMN2HTTNPC1POLB | |
| SCHEMBL437186 | 0.73 | KMT2A (0.51) | LMNASMN1; SMN2NPC1POLBKDM4E | |
| SCHEMBL12099914 | 0.73 | MAPT (0.51) | LMNASMN1; SMN2NPC1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391882-B1 | PSYCHOLOGICAL DISORDERS; ANTIDEPRESSANTS | H. LUNDBECK A/S (DK) | 2002-05-21 | — | — | US | disclosed |