Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550297 | 0.88 | GRIN1 (0.41) | MTNR1AMTNR1BKDM4EHSD17B10HPGD | |
| SCHEMBL7547159 | 0.87 | MTNR1A (0.36) | MTNR1AMTNR1BKDM4EHSD17B10HPGD | |
| SCHEMBL7648683 | 0.75 | GRIN1 (0.45) | LMNAMAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL7551094 | 0.72 | MTNR1A (0.34) | MTNR1AMTNR1BKDM4EHPGDLMNA | |
| SCHEMBL7657461 | 0.71 | ALOX15 (0.38) | KDM4EHSD17B10HPGDMAPTLMNA | |
| SCHEMBL7547267 | 0.71 | MTNR1A (0.32) | MTNR1AMTNR1BMAPTL3MBTL1 | |
| SCHEMBL7549570 | 0.70 | GRIN1 (0.52) | KDM4EHSD17B10HPGDMAPTSMN1; SMN2 | |
| SCHEMBL7549087 | 0.69 | SLC6A3 (0.38) | KDM4EHPGDMAPTTSHRALDH1A1 | |
| SCHEMBL7546750 | 0.69 | BRD4 (0.50) | HPGDALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL8122601 | 0.66 | ALDH1A1 (0.48) | KDM4EHSD17B10HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495587-B1 | TREATING A DAMAGE TO THE CENTRAL NERVOUS SYSTEM INDUCED BY AN ISCHEMIC OR HYPOXIC CONDITION AND STROKE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-12-17 | — | — | US | disclosed |