SCHEMBL7657743

SCHEMBL7657743

C#CCOc1nc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGPAT2 O15120 1/20 0.32
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7594681 0.88 HRH4 (0.36)
SCHEMBL7658216 0.86 EGFR (0.31) AGPAT2
SCHEMBL7837825 0.84 HTT (0.33)
SCHEMBL7594678 0.82
SCHEMBL29190282 0.82 DHODH (0.31)
SCHEMBL28991747 0.81 PPOX (0.40) NPSR1
SCHEMBL22361941 0.81 AGPAT2 (0.34) AGPAT2
SCHEMBL8924821 0.80 BCAT1 (0.35)
SCHEMBL7597082 0.80 GRM4 (0.31) NPSR1
SCHEMBL29435264 0.79 KAT2B (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6380134-B1 USED FOR CONTROLLING WEEDS SYNGENTA CROP PROTECTION, INC. 2002-04-30 US disclosed
EP-1084117-A2 NOVEL HERBICIDES Novartis AG (CH) 2001-03-21 EP disclosed
EP-1076655-A1 N-PYRIDONYL HERBICIDES Novartis AG (CH) 2001-02-21 EP disclosed
WO-1999052893-A1 N-PYRIDONYL HERBICIDES NOVARTIS AG (CH) 1999-10-21 WO disclosed
WO-1999052892-A2 NOVEL HERBICIDES NOVARTIS AG (CH) 1999-10-21 WO disclosed