Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525235 | 0.85 | ITGB3 (0.68) | ITGB3ITGA2BL3MBTL1L3MBTL3ITGAV | |
| SCHEMBL7366389 | 0.81 | TSHR (0.43) | ITGB3ITGA2BL3MBTL1TSHRITGAV | |
| SCHEMBL7078805 | 0.81 | TSHR (0.43) | ITGB3ITGA2BL3MBTL1TSHRITGAV | |
| SCHEMBL8144896 | 0.79 | ITGB3 (0.70) | ITGB3ITGA2BL3MBTL1L3MBTL3ITGAV | |
| SCHEMBL7910269 | 0.79 | ITGB3 (0.70) | ITGB3ITGA2BL3MBTL1L3MBTL3ITGAV | |
| SCHEMBL7919242 | 0.75 | TSHR (0.43) | ITGB3ITGA2BL3MBTL1TSHRALDH1A1 | |
| SCHEMBL7401266 | 0.75 | TSHR (0.43) | ITGB3ITGA2BL3MBTL1TSHRALDH1A1 | |
| SCHEMBL7368068 | 0.74 | CDK4 (0.51) | — | |
| SCHEMBL6677720 | 0.72 | ITGB3 (0.69) | ITGB3ITGA2BL3MBTL1L3MBTL3ITGAV | |
| Lotrafiban SCHEMBL4432242 | 0.72 | ITGB3 (0.96) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335330-B1 | 7-((4,4*-BIPIPERIDIN-1-YL)CARBONYL)-2,3,4,5-TETRAHYDRO-4--METH YL-3-OXO-1H-1,4-BENZODIAZEPINE-2-ACETIC ACID HYDROCHLORIDE; FIBRINOGEN RECEPTOR ANTAGONITS, ANTICOAGULANTS; PREVENTION OF STROKES, RESTENOSIS | SMITHKLINE BEECHAM CORPORATION | 2002-01-01 | — | — | US | disclosed |