Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.68 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.68 |
| ▸ | ITGAV | P06756 | 5/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658169 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BITGAVL3MBTL3L3MBTL1 | |
| SCHEMBL8525117 | 0.84 | ITGB3 (0.50) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677720 | 0.82 | ITGB3 (0.69) | ITGB3ITGA2BITGAVL3MBTL3L3MBTL1 | |
| Lotrafiban SCHEMBL29596 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| Lotrafiban SCHEMBL6673128 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| Lotrafiban SCHEMBL6673166 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| Lotrafiban SCHEMBL919968 | 0.80 | ITGB3 (0.98) | ITGB3ITGA2BITGAV | |
| SCHEMBL5155939 | 0.80 | ITGB3 (0.41) | ITGB3ITGA2BITGAV | |
| Lotrafiban SCHEMBL4432242 | 0.80 | ITGB3 (0.96) | ITGB3ITGA2BITGAV | |
| SCHEMBL8155059 | 0.75 | ITGB3 (0.59) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964928-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1999-12-22 | — | — | EP | claimed |
| WO-1998029561-A1 | ENZYMATIC RESOLUTION OF BENZODIAZEPINE-ACETIC ACID ESTERS WITH A LIPASE | SMITHKLINE BEECHAM PLC (GB) | 1998-07-09 | — | — | WO | claimed |