Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | IGFBP3 | P17936 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655633 | 0.88 | GRM2 (0.43) | MCL1CTNNB1KDM4EKMT2AMEN1 | |
| SCHEMBL7662426 | 0.86 | ADORA3 (0.43) | KDM4EKMT2AMEN1GAAPOLB | |
| SCHEMBL7656206 | 0.86 | NPC1 (0.43) | CTNNB1KDM4EKMT2AMEN1GAA | |
| SCHEMBL7656191 | 0.85 | CFTR (0.47) | MCL1KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7662205 | 0.83 | SIRT2 (0.53) | KDM4EKMT2AMEN1GAATP53 | |
| SCHEMBL7662979 | 0.81 | NPC1 (0.60) | KDM4EKMT2AMEN1GAATP53 | |
| SCHEMBL7652092 | 0.79 | ALDH1A1 (0.50) | CTNNB1KDM4EKMT2AMEN1GAA | |
| SCHEMBL7659132 | 0.78 | KMT2A (0.62) | KDM4EKMT2AMEN1POLBRXFP1 | |
| SCHEMBL7660819 | 0.77 | KDM4E (0.53) | CTNNB1KDM4EKMT2AMEN1GAA | |
| SCHEMBL7655836 | 0.76 | ALDH1A1 (0.50) | KDM4EKMT2AMEN1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |