Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655647 | 0.95 | MAPT (0.51) | ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7651397 | 0.91 | POLB (0.55) | ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7659132 | 0.86 | KMT2A (0.62) | ALDH1A1KMT2ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL7658391 | 0.83 | MAPT (0.45) | ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7655128 | 0.83 | RAB9A (0.52) | KMT2ASMN1; SMN2POLBMEN1MAPT | |
| SCHEMBL7662979 | 0.82 | NPC1 (0.60) | ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7662426 | 0.81 | ADORA3 (0.43) | ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7656191 | 0.80 | CFTR (0.47) | ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7659665 | 0.79 | GRM2 (0.54) | ALDH1A1HPGDKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL7657898 | 0.78 | SIRT2 (0.44) | ALDH1A1HPGDSMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | claimed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | claimed |
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |