Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659665 | 0.90 | GRM2 (0.54) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL7658391 | 0.88 | MAPT (0.45) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL7657898 | 0.86 | SIRT2 (0.44) | ALDH1A1KDM4EMAPTHPGDGRM2 | |
| SCHEMBL7655633 | 0.85 | GRM2 (0.43) | CFTRALDH1A1KDM4EMCL1KMT2A | |
| SCHEMBL7658200 | 0.85 | MCL1 (0.47) | ALDH1A1KDM4EMCL1MAPTHPGD | |
| SCHEMBL7655647 | 0.84 | MAPT (0.51) | ALDH1A1KDM4EMAPTHPGDRECQL | |
| SCHEMBL7659132 | 0.82 | KMT2A (0.62) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL7656725 | 0.81 | NR4A2 (0.45) | ALDH1A1KDM4EMAPTHPGDKMT2A | |
| SCHEMBL7651397 | 0.80 | POLB (0.55) | ALDH1A1KDM4EMAPTHPGDRECQL | |
| SCHEMBL7655836 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |