Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 4/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 7/20 | 0.40 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650152 | 0.86 | MLYCD (0.42) | MLYCDP4HTMP4HA1MIFMAPK1 | |
| SCHEMBL7109261 | 0.83 | MLYCD (0.31) | MLYCDL3MBTL1ALDH1A1 | |
| SCHEMBL7655871 | 0.82 | P4HTM (0.38) | MLYCDP4HTMP4HA1MIFMAPK1 | |
| SCHEMBL7656690 | 0.79 | P4HTM (0.43) | MLYCDP4HTMP4HA1MIFMAPK1 | |
| SCHEMBL10460373 | 0.77 | MLYCD (0.48) | MLYCDP4HTMP4HA1MIFMAPK1 | |
| SCHEMBL7658552 | 0.73 | CASP3 (0.34) | MLYCDKDM4EL3MBTL1ALDH1A1CFTR | |
| SCHEMBL7651870 | 0.73 | TDP1 (0.41) | MAPK1KDM4EL3MBTL1NPC1ALDH1A1 | |
| SCHEMBL7108508 | 0.73 | — | — | |
| SCHEMBL7655696 | 0.72 | P4HTM (0.40) | MLYCDP4HTMP4HA1MIFMAPK1 | |
| SCHEMBL7658471 | 0.72 | ROCK2 (0.39) | MLYCDP4HTMP4HA1MIFMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | claimed |
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | disclosed |