Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105124 | 0.81 | L3MBTL1 (0.41) | L3MBTL1NPC1ALDH1A1RAB9APOLB | |
| SCHEMBL8824764 | 0.81 | MLYCD (0.48) | P4HTMP4HA1MIFL3MBTL1MAPK1 | |
| SCHEMBL10460373 | 0.81 | MLYCD (0.48) | P4HTMP4HA1MIFL3MBTL1MAPK1 | |
| SCHEMBL7655050 | 0.80 | HDAC4 (0.44) | P4HTMP4HA1MIFL3MBTL1MAPK1 | |
| SCHEMBL7157289 | 0.79 | ALDH1A1 (0.48) | L3MBTL1MLYCDNPC1ALDH1A1LIMK2 | |
| SCHEMBL7658682 | 0.79 | MLYCD (0.43) | P4HTMP4HA1MIFL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL3666665 | 0.79 | P4HA1 (0.37) | P4HTMP4HA1MIFMAPK1MLYCD | |
| SCHEMBL8824838 | 0.79 | CFTR (0.46) | P4HTMNPC1RAB9A | |
| SCHEMBL7650152 | 0.78 | MLYCD (0.42) | P4HTMP4HA1MIFL3MBTL1MAPK1 | |
| SCHEMBL8824711 | 0.76 | SMN1; SMN2 (0.41) | P4HTMP4HA1MIFL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | claimed |
| WO-2020184628-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | 日産化学株式会社 | 2020-09-17 | — | — | WO | disclosed |
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | disclosed |