Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 5/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10081644 | 0.89 | DNMT1 (0.49) | DNMT1ADRB1DNMT3B | |
| SCHEMBL6229367 | 0.86 | POLG (0.46) | — | |
| SCHEMBL6229380 | 0.86 | POLG (0.46) | — | |
| Phosphoric Acid SCHEMBL8417569 | 0.86 | DNMT1 (0.53) | DNMT1ADRB1DNMT3B | |
| SCHEMBL2119433 | 0.84 | DNMT1 (0.49) | DNMT1ADRB1DNMT3B | |
| SCHEMBL22219920 | 0.84 | DNMT1 (0.49) | DNMT1ADRB1DNMT3B | |
| SCHEMBL25754118 | 0.84 | DNMT1 (0.49) | DNMT1ADRB1DNMT3B | |
| SCHEMBL2119424 | 0.84 | DNMT1 (0.49) | DNMT1ADRB1DNMT3B | |
| SCHEMBL2611588 | 0.84 | DNMT1 (0.49) | DNMT1ADRB1DNMT3B | |
| SCHEMBL17152993 | 0.82 | DNMT1 (0.51) | DNMT1ADRB1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437141-B2 | FOR LABELING TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-20010020098-A1 | For labeling target molecules | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-09-06 | — | — | US | disclosed |
| US-6224644-B1 | CYANINE DYES INCLUDES FREE OR PROTECTED THIOL, AMINE OR HYDROXY SUBSTITUENT CAPABLE OF REACTING WITH A TARGET MOLECULE THROUGH A NEUCLOPHILIC DISPLACEMENT, USEFUL IN LABELING A VARIETY OF TARGET MOLECULES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6204389-B1 | DEBLOCKING; NUCLEOPHILIC DISPLACEMENT | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6197956-B1 | FLUORESCENT BENZIMIDAZOLE, BENZOTHIAZOLE, BENZOXAZOLE, BENZOTHIAZINE, BENZOXAZINE AND QUINOLINE DYES | NEN LIFE SCIENCE PRODUCTS, INC. | 2001-03-06 | — | — | US | disclosed |
| US-6114350-A | Cyanine dyes and synthesis methods thereof | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020098-A1 | For labeling target molecules | CYC1, THEM6, TPH1 | ADRB1 147/4885DNMT1 1941/4885DNMT3B 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.