Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.67 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.67 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206716 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1HPGDSMN1; SMN2MITF | |
| Hydrochloric Acid SCHEMBL11768179 | 0.98 | KDM4E (0.65) | KDM4EALDH1A1HPGDSMN1; SMN2MITF | |
| SCHEMBL7966311 | 0.95 | KDM4E (0.70) | KDM4EALDH1A1HPGDSMN1; SMN2MITF | |
| SCHEMBL7966308 | 0.95 | KDM4E (0.70) | KDM4EALDH1A1HPGDSMN1; SMN2MITF | |
| SCHEMBL1206905 | 0.89 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDSMN1; SMN2MITF | |
| SCHEMBL28614845 | 0.89 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDSMN1; SMN2MITF | |
| SCHEMBL1206901 | 0.89 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDSMN1; SMN2MITF | |
| SCHEMBL846032 | 0.88 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL846033 | 0.88 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11763070 | 0.88 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5961875-A | Antifreeze/coolant composition containing cinnamic acid | CCI CO., LTD. (JP) | 1999-10-05 | — | — | US | claimed |
| EP-4619378-A2 | IONIZABLE LIPIDS AND LIPID NANOPARTICLE COMPOSITIONS FOR THE DELIVERY OF NUCLEIC ACIDS | Seawolf Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-120202184-A | Ionizable lipids and lipid nanoparticle compositions for delivery of nucleic acids | 海狼治疗公司 | 2025-06-24 | — | — | CN | disclosed |
| WO-2024107906-A2 | IONIZABLE LIPIDS AND LIPID NANOPARTICLE COMPOSITIONS FOR THE DELIVERY OF NUCLEIC ACIDS | SEAWOLF THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024107906-A2 | IONIZABLE LIPIDS AND LIPID NANOPARTICLE COMPOSITIONS FOR THE DELIVERY OF NUCLEIC ACIDS | SEAWOLF THERAPEUTICS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| US-11253596-B2 | Phenylalkylcarboxylic acid delivery agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2022-02-22 | — | — | US | disclosed |
| US-20200405863-A1 | PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS | NOVO NORDISK A/S (DK) | 2020-12-31 | — | — | US | disclosed |
| US-10456472-B2 | Phenylalkylcarboxylic acid delivery agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2019-10-29 | — | — | US | disclosed |
| EP-2114145-B1 | PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS | EMISPHERE TECH INC (US) | 2017-11-01 | — | — | EP | disclosed |
| US-20160375135-A1 | PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2016-12-29 | — | — | US | disclosed |
| US-5708018-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| US-5539074-A | LIQUID CRYSTAL POLYMERS ON SILICA FOR LIGHT SENSITIVE ELEMENTS | HOFFMANN-LA ROCHE INC. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0712387-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004713-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | THE UPJOHN COMPANY (US) | 1995-02-16 | — | — | WO | disclosed |
| US-RE32944-E | Aromatic carboxylic amide derivatives | Kissei Yakuhin Kogyo Kabushiki (JP) | 1989-06-06 | — | — | US | disclosed |
| US-4070484-A | Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same | KISSEI PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |
| US-4061587-A | Liquid crystalline cinnamic acid esters | HOFFMANN-LA ROCHE INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4026896-A | ANTIALLERGENS | KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (KISSEI PHARMACEUTICAL CO. LTD.) (JA) | 1977-05-31 | — | — | US | disclosed |
| US-3962219-A | DISTYRYL-BENZOBISOXAZOLES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
| US-3940422-A | ANTIALLERGEN | KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (JA) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200405863-A1 | PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS | PGF, LIPA, PDGFA | KDM4E 2723/4885ALDH1A1 599/4885HPGD 1242/4885 |
| US-10456472-B2 | Phenylalkylcarboxylic acid delivery agents | PGF, LIPA, PDGFA | KDM4E 2723/4885ALDH1A1 599/4885HPGD 1242/4885 |
| US-11253596-B2 | Phenylalkylcarboxylic acid delivery agents | PGF, LIPA, PDGFA | KDM4E 2723/4885ALDH1A1 599/4885HPGD 1242/4885 |
| US-20160375135-A1 | PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS | PGF, LIPA, PDGFA | KDM4E 2723/4885ALDH1A1 599/4885HPGD 1242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.