Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906856 | 0.80 | ALDH1A1 (0.48) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL23666646 | 0.72 | L3MBTL1 (0.57) | RAB9ANPC1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17445193 | 0.68 | TRPM8 (0.39) | RAB9ANPC1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6907276 | 0.68 | MAPK1 (0.53) | RAB9ANPC1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL7062575 | 0.68 | MAPK1 (0.40) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2772081 | 0.67 | RAB9A (0.50) | RAB9ANPC1KDM4EALDH1A1EGFR | |
| SCHEMBL374899 | 0.67 | KMT2A (0.46) | RAB9ANPC1KDM4EEGFRERBB2 | |
| SCHEMBL7158819 | 0.67 | L3MBTL1 (0.64) | RAB9ANPC1KDM4EALDH1A1EGFR | |
| SCHEMBL22908698 | 0.67 | ALDH1A1 (0.53) | RAB9ANPC1KDM4EALDH1A1CACNA1B | |
| SCHEMBL9963324 | 0.66 | CYP2D6 (0.40) | NPC1KDM4EL3MBTL1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376492-B1 | GUANIDINE DERIVATIVES | MEDIVIR AB (SE) | 2002-04-23 | — | — | US | disclosed |