Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.62 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9301872 | 0.82 | ALOX5 (0.56) | ALOX5TOP2AESRRBESRRA | |
| SCHEMBL8081262 | 0.81 | ALOX5 (0.62) | ALOX5TOP2APDE1APDE1BPDE3B | |
| SCHEMBL16272594 | 0.77 | ALOX5 (1.00) | ALOX5TOP2APDE1APDE1BPDE3B | |
| SCHEMBL7656932 | 0.76 | ALOX5 (0.54) | ALOX5TOP2A | |
| SCHEMBL7651428 | 0.75 | ALOX5 (0.50) | ALOX5MAOAMAOBCA12CA1 | |
| SCHEMBL29582148 | 0.71 | ALOX5 (1.00) | ALOX5TOP2APDE1APDE1BPDE3B | |
| SCHEMBL30637547 | 0.71 | ALOX5 (1.00) | ALOX5TOP2APDE1APDE1BPDE3B | |
| SCHEMBL7659399 | 0.71 | ALOX5 (1.00) | ALOX5TOP2APDE1APDE1BPDE3B | |
| SCHEMBL9125611 | 0.69 | ALOX5 (0.56) | ALOX5TOP2A | |
| SCHEMBL38656885 | 0.69 | ALOX5 (0.72) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0975621-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998049155-A1 | CELL DIFFERENTIATION INDUCING AMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-05 | — | — | WO | disclosed |