Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 12/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664768 | 0.94 | CAMK2D (0.46) | CAMK2DKDRGSK3BPIM1 | |
| SCHEMBL7654522 | 0.87 | ALDH1A1 (0.42) | ALDH1A1PRKCBPRKCAPRKCHPRKCQ | |
| SCHEMBL7658933 | 0.86 | PDE4B (0.46) | CAMK2DKDRGSK3B | |
| SCHEMBL7657926 | 0.86 | USP2 (0.41) | USP2ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7662878 | 0.86 | ACKR3 (0.36) | CAMK2DUSP2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7656438 | 0.85 | CAMK2D (0.42) | CAMK2DKDRGSK3BPIM1 | |
| SCHEMBL7662107 | 0.84 | CAMK2D (0.45) | CAMK2DKDRGSK3BUSP2ALDH1A1 | |
| SCHEMBL7655234 | 0.84 | CAMK2D (0.40) | CAMK2DKDRGSK3BUSP2ALDH1A1 | |
| SCHEMBL7665495 | 0.83 | CAMK2D (0.41) | CAMK2DKDRGSK3BPIM1 | |
| SCHEMBL7664149 | 0.83 | CAMK2D (0.41) | CAMK2DKDRGSK3BPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071683-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2001-01-31 | — | — | EP | claimed |
| WO-1999046264-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| US-6458792-B1 | MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. | ASTRAZENECA AB (SE) | 2002-10-01 | — | — | US | disclosed |
| EP-1071683-A1 | NEW COMPOUNDS | AstraZeneca AB (SE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999046264-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |