Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.67 |
| ▸ | HTR2B | P41595 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDR | P35968 | 4/20 | 0.56 |
| ▸ | CLK2 | P49760 | 4/20 | 0.56 |
| ▸ | HIPK4 | Q8NE63 | 4/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.56 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.56 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.56 |
| ▸ | CDK2 | P24941 | 3/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7659686 | 0.85 | RAB9A (0.58) | HTR2CHTR2BMEN1KMT2AGAA | |
| SCHEMBL7370903 | 0.84 | HTR2C (0.70) | HTR2CHTR2BMEN1KMT2AMAPT | |
| SCHEMBL7375771 | 0.83 | HTR2C (0.81) | HTR2CHTR2BMEN1KMT2AKDM4E | |
| SCHEMBL7447310 | 0.83 | HTR2C (0.67) | HTR2CHTR2BMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7655749 | 0.82 | HTR2C (0.65) | HTR2CHTR2BKDM4EALDH1A1KDR | |
| SCHEMBL7369676 | 0.81 | HTR2C (0.78) | HTR2CHTR2BKDM4EMAPTKDR | |
| SCHEMBL7454585 | 0.81 | HTR2C (0.77) | HTR2CHTR2BMEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL7655770 | 0.81 | HTR2C (0.77) | HTR2CHTR2BKDRCLK2HIPK4 | |
| SCHEMBL27579461 | 0.80 | PLK4 (0.73) | HTR2CHTR2BMEN1KMT2AKDM4E | |
| SCHEMBL19427718 | 0.80 | MAPT (0.79) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | claimed |
| US-6410529-B1 | DIETETICS; NON-INSULIN DEPENDENT DIABETES; SLEEP DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-06-25 | — | — | US | disclosed |