SCHEMBL850782

SCHEMBL850782

O=C1CCC(C(=O)OCc2ccccc2)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.51
FABP5 Q01469 1/20 0.51
CYP2C19 P33261 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
HPGD P15428 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
TSHR P16473 2/20 0.48
ALDH1A1 P00352 4/20 0.48
GAA P10253 1/20 0.48
FKBP1A P62942 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
KMT2A Q03164 1/20 0.46
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564309 0.91 CYP2C19 (0.56) FABP7FABP5CYP2C19CYP3A4CYP2C9
SCHEMBL13452120 0.91 CYP2C19 (0.56) FABP7FABP5CYP2C19CYP3A4CYP2C9
SCHEMBL16001109 0.91 CYP2C19 (0.56) FABP7FABP5CYP2C19CYP3A4CYP2C9
SCHEMBL280126 0.88 FABP7 (0.58) FABP7FABP5CYP2C19HPGDSMN1; SMN2
SCHEMBL10917021 0.88 FABP7 (0.58) FABP7FABP5CYP2C19HPGDSMN1; SMN2
SCHEMBL6666657 0.88 FABP7 (0.58) FABP7FABP5CYP2C19HPGDSMN1; SMN2
SCHEMBL17365604 0.88 CYP3A4 (0.53) FABP7FABP5CYP2C19CYP3A4CYP2C9
SCHEMBL11982183 0.88 CYP3A4 (0.53) FABP7FABP5CYP2C19CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL27944947 0.86 FABP7 (0.57) FABP7FABP5CYP2C19HPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL27765522 0.86 FABP7 (0.57) FABP7FABP5CYP2C19HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865889-A Synthesis method of benzisoquinoline compound 山东省药学科学院 2024-04-12 CN claimed
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI-AVENTIS RECHERCHE & DÉVELOPPEMENT (FR) 2026-01-22 US disclosed
US-20250223289-A1 INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN SCHRODINGER, INC. 2025-07-10 US disclosed
EP-4558500-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-05-28 EP disclosed
US-20250129067-A1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF PROGENTOS THERAPEUTICS, INC. (US) 2025-04-24 US disclosed
US-12227496-B2 Substituted bicyclic compounds as farnesoid X receptor modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2025-02-18 US disclosed
US-12145935-B2 Inhibitors of (α-v)(β-6) integrin MORPHIC THERAPEUTIC, INC. (US) 2024-11-19 US disclosed
EP-4430047-A1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF Progentos Therapeutics, Inc. (US) 2024-09-18 EP disclosed
CN-118475580-A Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof 普罗根托斯治疗公司 2024-08-09 CN disclosed
CN-117865889-A Synthesis method of benzisoquinoline compound 山东省药学科学院 2024-04-12 CN disclosed
US-20110274655-A1 TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE Infinity Pharmaceuticals (US) 2011-11-10 US disclosed
US-7816380-B2 1-hydroxycycloalkanecarboxamide derivatives MERCK SHARP & DOHME CORP. (US) 2010-10-19 US disclosed
EP-1758949-B1 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP AND SULFONIC ACID GROUP, AND PRODUCTION METHOD THEREOF CANON KK (JP) 2010-01-13 EP disclosed
US-20090062349-A1 1-Hydroxycycloalkanecarboxamide derivatives MERCK SHARP & DOHME LLC 2009-03-05 US disclosed
US-7465779-B2 Polyhydroxyalkanoate having vinyl group, ester group, carboxyl group and sulfonic acid group, and production method thereof CANON KABUSHIKI KAISHA (JP) 2008-12-16 US disclosed
EP-1893579-A1 1-HYDROXYCYCLOALKANECARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS Merck & Co., Inc. (US) 2008-03-05 EP disclosed
EP-1758949-A2 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP AND SULFONIC ACID GROUP, AND PRODUCTION METHOD THEREOF Canon Kabushiki Kaisha (JP) 2007-03-07 EP disclosed
WO-2006132837-A1 l-HYDROXYCYCLOALKANECARBOXAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS MERCK & CO., INC. (US) 2006-12-14 WO disclosed
US-20060247414-A1 Polyhydroxyalkanoate having vinyl group, ester group, carboxyl group and sulfonic acid group, and production method thereof CANON KABUSHIKI KAISHA (JP) 2006-11-02 US disclosed
WO-2005121206-A2 POLYHYDROXYALKANOATE HAVING VINYL GROUP, ESTER GROUP, CARBOXYL GROUP AND SULFONIC ACID GROUP, AND PRODUCTION METHOD THEREOF CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12227496-B2 Substituted bicyclic compounds as farnesoid X receptor modulators FXR1, NR1H4, FXR2 FABP7 1183/4885FABP5 390/4885CYP2C19 1139/4885
US-20110274655-A1 TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE FASN, ACSL1, HSD17B12 FABP7 380/4885FABP5 79/4885CYP2C19 1203/4885
US-20250223289-A1 INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN ITGB6, ITGA6, ITGAV FABP7 3401/4885FABP5 2911/4885CYP2C19 4574/4885
US-12145935-B2 Inhibitors of (α-v)(β-6) integrin ITGB6, ITGA6, ITGAV FABP7 3399/4885FABP5 2748/4885CYP2C19 4665/4885
US-20250129067-A1 PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF PDGFRB, PDGFRA, PDGFA FABP7 409/4885FABP5 1986/4885CYP2C19 4779/4885
US-20090062349-A1 1-Hydroxycycloalkanecarboxamide derivatives BDKRB1, BDKRB2, HRH4 FABP7 3029/4885FABP5 3377/4885CYP2C19 1573/4885
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF MAPK1, MAPK3, MAPK6 FABP7 4248/4885FABP5 1626/4885CYP2C19 2599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.