Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656754 | 0.86 | SIGMAR1 (0.51) | SIGMAR1HPGDALDH1A1CA1CA2 | |
| SCHEMBL2628902 | 0.81 | SIGMAR1 (0.55) | SIGMAR1HPGDALDH1A1KDM4EBLM | |
| SCHEMBL27799875 | 0.81 | SIGMAR1 (0.58) | SIGMAR1HPGDALDH1A1KDM4ECA1 | |
| SCHEMBL27854131 | 0.81 | SIGMAR1 (0.58) | SIGMAR1HPGDALDH1A1KDM4ECA1 | |
| SCHEMBL3306996 | 0.81 | MAPT (0.39) | ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL12261946 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAAPOLB | |
| SCHEMBL9781792 | 0.80 | PKM (0.50) | ALDH1A1GAAPOLB | |
| SCHEMBL28278676 | 0.78 | CA1 (0.57) | SIGMAR1HPGDBLMCA1CA2 | |
| SCHEMBL7801902 | 0.78 | L3MBTL1 (0.54) | SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL1658469 | 0.77 | KDM4E (0.46) | HPGDALDH1A1KDM4ETSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469006-B1 | PARTICULARLY FOR TREATING HIV INFECTIONS | BRISTOL-MYERS SQUIBB COMPANY | 2002-10-22 | — | — | US | disclosed |
| EP-1105135-A4 | ANTIVIRAL INDOLEOXOACETYL PIPERAZINE DERIVATIVES | BRISTOL MYERS SQUIBB CO (US) | 2001-12-12 | — | — | EP | disclosed |
| CN-1320037-A | Antiviral indoloxoacetylpiperazine derivatives | BRISTOL MYERS SQUIBB CO (US) | 2001-10-31 | — | — | CN | disclosed |
| EP-1105135-A1 | ANTIVIRAL INDOLEOXOACETYL PIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000076521-A1 | ANTIVIRAL INDOLEOXOACETYL PIPERAZINE DERIVATIVES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |