SCHEMBL7660405

SCHEMBL7660405

c1ccc2c(c1)CC1CC2O1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 2/20 0.42
CHRNA4 P43681 2/20 0.42
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
SIGMAR1 Q99720 2/20 0.39
KDM1A O60341 4/20 0.38
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
HRH3 Q9Y5N1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5693155 0.79 GRIN2D (0.43) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1
SCHEMBL1036653 0.75 CHRNB2 (0.45) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1
SCHEMBL2370159 0.68 KMT2A (0.46) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1
SCHEMBL8201616 0.68 KMT2A (0.46) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1
SCHEMBL5061699 0.68 KMT2A (0.46) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1
SCHEMBL2696782 0.68 KMT2A (0.46) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1
SCHEMBL5693132 0.67 CHRNB2 (0.54) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1
SCHEMBL6410879 0.66 CHRNB2 (0.36) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1
SCHEMBL29032068 0.64 L3MBTL4 (0.43) SIGMAR1HTR2AHTR2CHTR2BHRH3
SCHEMBL20384849 0.64 KMT2A (0.42) CHRNB2CHRNA4GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11753503-B2 Supported onium salts as initiators for the synthesis of polycarbonates by copolymerization of CO2 with epoxides KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2023-09-12 US disclosed
WO-2023288020-A1 COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS AVANTI BIOSCIENCES INC. (US) 2023-01-19 WO disclosed
US-20220010060-A1 POLYCARBONATE POLYOLS UNIV KING ABDULLAH SCI & TECH (SA) 2022-01-13 US disclosed
US-20210309801-A1 ETHYLENE OXIDE-BASED COPOLYMERS KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) 2021-10-07 US disclosed
US-20210179858-A1 POLYMERS, PROCESSES, COMPOSITIONS & USES DSM IP ASSETS B.V. (NL) 2021-06-17 US disclosed
US-10442892-B2 Copolymerization of carbon dioxide and cyclic monomers to form polycarbonates KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2019-10-15 US disclosed
US-20180051134-A1 COPOLYMERIZATION OF CARBON DIOXIDE AND CYCLIC MONOMERS TO FORM POLYCARBONATES KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2018-02-22 US disclosed
US-9550788-B2 Substituted aminoindanes and analogs thereof, and the pharmaceutical use thereof SANOFI (FR) 2017-01-24 US disclosed
US-6340704-B1 TREATING NERVE DISEASE OR BONE/JOINT DISEASE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-01-22 US disclosed