Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660405 | 0.66 | CHRNB2 (0.42) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5693155 | 0.62 | GRIN2D (0.43) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8201616 | 0.61 | KMT2A (0.46) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2696782 | 0.61 | KMT2A (0.46) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5061699 | 0.61 | KMT2A (0.46) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL2370159 | 0.61 | KMT2A (0.46) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29032068 | 0.61 | L3MBTL4 (0.43) | SIGMAR1 | |
| SCHEMBL15726594 | 0.60 | KMT2A (0.35) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1036653 | 0.60 | CHRNB2 (0.45) | CHRNB2CHRNA4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8021997 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872840-B1 | Synthesis of 8-membered carbocyclic compound having diexomethylene groups | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-03-29 | — | — | US | claimed |
| US-20050059732-A1 | SYNTHESIS OF 8-MEMBERED CARBOCYCLIC COMPOUND HAVING DIEXOMETHYLENE GROUPS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2005-03-17 | — | — | US | claimed |
| US-6872840-B1 | Synthesis of 8-membered carbocyclic compound having diexomethylene groups | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-03-29 | — | — | US | disclosed |
| US-20050059732-A1 | SYNTHESIS OF 8-MEMBERED CARBOCYCLIC COMPOUND HAVING DIEXOMETHYLENE GROUPS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059732-A1 | SYNTHESIS OF 8-MEMBERED CARBOCYCLIC COMPOUND HAVING DIEXOMETHYLENE GROUPS | LTC4S, KARS1, C1S | CHRNB2 4516/4885CHRNA4 4345/4885GRIN2D 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.