SCHEMBL766044

SCHEMBL766044

Cc1cc(/C=C/C(=O)N2CCCCC2)c(OC(=O)OC(C)(C)C)cc1C

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.45
ALDH1A1 P00352 6/20 0.43
MAPT P10636 4/20 0.43
KMT2A Q03164 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 2/20 0.43
TRPV1 Q8NER1 1/20 0.42
PELI1 Q96FA3 3/20 0.41
BCHE P06276 3/20 0.40
MAOA P21397 3/20 0.40
ACHE P22303 3/20 0.40
MAOB P27338 3/20 0.40
PTGS2 P35354 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13087409 0.91 HPGD (0.50) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL766065 0.89 HPGD (0.41) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL13087048 0.88 TRPV1 (0.47) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL10227977 0.87 HPGD (0.53) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL766030 0.86 HPGD (0.49) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL766038 0.85 ALDH1A1 (0.47) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL766051 0.84 TRPV1 (0.51) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL766006 0.84 PELI1 (0.56) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL766018 0.83 HPGD (0.46) HPGDALDH1A1MAPTKMT2ARAB9A
SCHEMBL766028 0.82 HPGD (0.65) HPGDALDH1A1MAPTKMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120070781-A1 BASE GENERATOR, PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING MATERIAL COMPRISING THE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD USING THE PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCTS COMPRISING THE SAME RER1, SUN2, REV1 HPGD 861/4885ALDH1A1 2053/4885MAPT 852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.