SCHEMBL7660973

SCHEMBL7660973

CN(C(=O)OC(C)(C)C)[C@@H](COCCO)Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.41
MAOB P27338 1/20 0.41
ATM Q13315 1/20 0.39
ITGA4 P13612 1/20 0.38
ITGB7 P26010 1/20 0.38
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
OPRK1 P41145 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CTSS P25774 3/20 0.37
CTSL P07711 2/20 0.37
CTSB P07858 2/20 0.37
CTSK P43235 1/20 0.37
MMP13 P45452 1/20 0.37
PPARA Q07869 1/20 0.37
REN P00797 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6317409 0.88 MAOB (0.45) L3MBTL1MAOBATMITGA4ITGB7
SCHEMBL7162284 0.88 MAOB (0.45) L3MBTL1MAOBATMITGA4ITGB7
SCHEMBL27489128 0.84 ATM (0.43) L3MBTL1ATMITGA4ITGB7OPRM1
SCHEMBL6316889 0.84 ATM (0.43) L3MBTL1ATMITGA4ITGB7OPRM1
SCHEMBL2473923 0.84 ATM (0.43) L3MBTL1ATMITGA4ITGB7OPRM1
SCHEMBL7659205 0.83 GHSR (0.43) MAOBCTSSCTSBCTSKMMP13
SCHEMBL7655537 0.82 TSHR (0.40) L3MBTL1MAOBATMITGA4ITGB7
SCHEMBL8907586 0.82 L3MBTL1 (0.43) L3MBTL1ATMITGA4ITGB7OPRM1
SCHEMBL6316448 0.81 ATM (0.42) L3MBTL1ATMITGA4ITGB7OPRM1
SCHEMBL4864100 0.80 NPSR1 (0.48) L3MBTL1MAOBNPSR1CTSSPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6350767-B1 GROWTH HORMONE RELEASE STIMULANT NOVO NORDISK A/S (DK) 2002-02-26 US disclosed
US-6013658-A ANIMAL GROWTH REGULATORS NOVO NORDISK A/S (DK) 2000-01-11 US disclosed
WO-1996022997-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1996-08-01 WO disclosed