Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9247903 | 0.79 | GABBR2 (0.37) | CYP1A2GABBR2GABBR1 | |
| SCHEMBL11022417 | 0.78 | ESR1 (0.35) | MIF | |
| SCHEMBL136577 | 0.77 | HTR2A (0.41) | GABBR2GABBR1 | |
| SCHEMBL146771 | 0.76 | MTNR1A (0.55) | MTNR1AMTNR1BCYP19A1EPHX1ACP3 | |
| SCHEMBL693020 | 0.75 | CYP1A2 (0.37) | EPHX1SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL2791745 | 0.75 | GABBR2 (0.34) | CYP1A2GABBR2GABBR1 | |
| SCHEMBL28696042 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BCYP19A1EPHX1ACP3 | |
| Hydrochloric Acid SCHEMBL30185866 | 0.74 | MTNR1A (0.53) | MTNR1AMTNR1BCYP19A1EPHX1ACP3 | |
| SCHEMBL9852986 | 0.72 | MTNR1A (0.53) | MTNR1AMTNR1BCYP19A1EPHX1ACP3 | |
| SCHEMBL6553384 | 0.72 | GABBR2 (0.63) | MTNR1AMTNR1BEPHX1ACP3MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335324-B1 | TREATING ASTHMA OR ALLERGIC RHINITIS | BRISTOL-MYERS SQUIBB CO. | 2002-01-01 | — | — | US | disclosed |