Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662201 | 0.89 | FNTA (0.35) | NAMPTCYP19A1POLBPTGS2FNTA | |
| SCHEMBL7658756 | 0.83 | FNTA (0.49) | NAMPTCYP19A1POLBFNTAFNTB | |
| SCHEMBL7653727 | 0.71 | FNTA (0.54) | CYP19A1FNTAFNTB | |
| SCHEMBL7657870 | 0.71 | FNTA (0.53) | CYP19A1FNTAFNTB | |
| SCHEMBL7664955 | 0.69 | CYP19A1 (0.45) | NAMPTCYP19A1POLBLMNA | |
| SCHEMBL7658747 | 0.68 | FNTA (0.46) | PTGS2FNTAFNTBCYP51A1ALOX15 | |
| SCHEMBL7667718 | 0.68 | CYP19A1 (0.40) | NAMPTCYP19A1POLBPTGS2LMNA | |
| SCHEMBL7653592 | 0.67 | FNTA (0.41) | CYP19A1PTGS2FNTAFNTBCYP51A1 | |
| SCHEMBL7561794 | 0.65 | FNTA (0.40) | NAMPTCYP19A1POLBPTGS2FNTA | |
| SCHEMBL7656241 | 0.65 | CYP51A1 (0.40) | PTGS2FNTAFNTBCYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410539-B1 | ANTICARCINOGENIC AGENTS | ASTRAZENCA UK LIMITED (GB) | 2002-06-25 | — | — | US | claimed |