Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960451 | 0.78 | MAPT (0.71) | NPC1RAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL7671720 | 0.77 | PKM (0.56) | LMNAMAPTL3MBTL1HTTALDH1A1 | |
| SCHEMBL4912964 | 0.76 | NPC1 (0.80) | NPC1RAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL30926697 | 0.76 | F10 (0.64) | LMNAMAPTHTTALDH1A1 | |
| SCHEMBL27180977 | 0.76 | F10 (0.64) | LMNAMAPTHTTALDH1A1 | |
| SCHEMBL8625175 | 0.75 | FLT1 (0.64) | NPC1RAB9ALMNAL3MBTL1HTT | |
| SCHEMBL17102977 | 0.75 | MEN1 (0.69) | NPC1RAB9ALMNAMAPTHTT | |
| SCHEMBL4293558 | 0.74 | ALDH1A1 (0.80) | NPC1RAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL12555378 | 0.74 | NPC1 (0.64) | NPC1RAB9ALMNAMAPTL3MBTL1 | |
| SCHEMBL17103006 | 0.74 | MEN1 (0.64) | LMNAMAPTHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1072587-A1 | SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Hidaka, Hiroyoshi (JP) | 2001-01-31 | — | — | EP | disclosed |