Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TK1 | P04183 | 3/20 | 0.42 |
| ▸ | TK2 | O00142 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14570606 | 0.85 | ADRB1 (0.47) | DNMT1ADRB1SMN1; SMN2LMNATK1 | |
| SCHEMBL889695 | 0.85 | ADRB1 (0.47) | DNMT1ADRB1SMN1; SMN2LMNATK1 | |
| SCHEMBL12123502 | 0.85 | ADRB1 (0.47) | DNMT1ADRB1SMN1; SMN2LMNATK1 | |
| SCHEMBL23786492 | 0.85 | ADRB1 (0.47) | DNMT1ADRB1SMN1; SMN2LMNATK1 | |
| SCHEMBL21206282 | 0.80 | ADRB1 (0.52) | DNMT1ADRB1SMN1; SMN2LMNATK1 | |
| SCHEMBL14303199 | 0.80 | DNMT1 (0.47) | DNMT1ADRB1SMN1; SMN2LMNAPNP | |
| SCHEMBL7666938 | 0.78 | PDE4D (0.60) | DNMT1ADRB1SMN1; SMN2LMNAPNP | |
| SCHEMBL7666946 | 0.78 | PDE4D (0.60) | DNMT1ADRB1SMN1; SMN2LMNAPNP | |
| SCHEMBL12541656 | 0.78 | ADRB1 (0.46) | DNMT1ADRB1SMN1; SMN2LMNATK1 | |
| SCHEMBL9205122 | 0.77 | TK1 (0.45) | DNMT1ADRB1SMN1; SMN2LMNATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498241-B1 | 2-deoxy-isoguanosines isosteric analogues and isoguanosine derivatives as well as their synthesis | ROCHE DIAGNOSTICS GMBH (DE) | 2002-12-24 | — | — | US | disclosed |