Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | TK2 | O00142 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205135 | 1.00 | TK1 (0.45) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL23786492 | 0.81 | ADRB1 (0.47) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL14570606 | 0.81 | ADRB1 (0.47) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL12123502 | 0.81 | ADRB1 (0.47) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL889695 | 0.81 | ADRB1 (0.47) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL9211927 | 0.80 | TK1 (0.50) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL9211924 | 0.80 | TK1 (0.50) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL8343204 | 0.79 | ADRB1 (0.57) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL1738505 | 0.79 | ADRB1 (0.57) | TK1LMNASMN1; SMN2ADRB1DNMT1 | |
| SCHEMBL7663097 | 0.77 | DNMT1 (0.47) | TK1LMNASMN1; SMN2ADRB1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286028-B1 | Derivatives of disazapurine nucleosides, process for their preparation and their use in the sequence analysis of nucleic acids and as antiviral agents | BOEHRINGER MANNHEIM GMBH (DE) | 1995-06-28 | — | — | EP | claimed |
| EP-0286028-B1 | Derivatives of disazapurine nucleosides, process for their preparation and their use in the sequence analysis of nucleic acids and as antiviral agents | BOEHRINGER MANNHEIM GMBH (DE) | 1995-06-28 | — | — | EP | disclosed |