SCHEMBL14570606

SCHEMBL14570606

Nc1nc2c(cnn2C2CC(O)C(CO)O2)c(=O)[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADRB1 P08588 1/20 0.47
▸ DNMT1 P26358 1/20 0.47
▸ LMNA P02545 3/20 0.44
▸ SMN1; SMN2 Q16637 3/20 0.44
▸ TK1 P04183 3/20 0.44
▸ TK2 O00142 1/20 0.43
▸ PNP P00491 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ HTT P42858 1/20 0.43
▸ PDE4D Q08499 1/20 0.43
▸ PDE3A Q14432 1/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.43
▸ POLA1 P09884 1/20 0.42
▸ ALOX12 P18054 1/20 0.42
▸ ADRA1A P35348 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ CYP1A2 P05177 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ BLM P54132 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL889695 1.00 ADRB1 (0.47) ADRB1DNMT1LMNASMN1; SMN2TK1
SCHEMBL12123502 1.00 ADRB1 (0.47) ADRB1DNMT1LMNASMN1; SMN2TK1
SCHEMBL23786492 1.00 ADRB1 (0.47) ADRB1DNMT1LMNASMN1; SMN2TK1
SCHEMBL7663097 0.85 DNMT1 (0.47) ADRB1DNMT1LMNASMN1; SMN2TK1
SCHEMBL12541656 0.82 ADRB1 (0.46) ADRB1DNMT1LMNASMN1; SMN2TK1
SCHEMBL9205135 0.81 TK1 (0.45) ADRB1DNMT1LMNASMN1; SMN2TK1
SCHEMBL9205122 0.81 TK1 (0.45) ADRB1DNMT1LMNASMN1; SMN2TK1
SCHEMBL31753101 0.81 POLB (0.56) POLB
SCHEMBL12650020 0.81 ALDH1A1 (0.45) LMNAPNP
SCHEMBL6062703 0.81 ADRB1 (0.45) ADRB1DNMT1LMNASMN1; SMN2TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4733412-A2 METHOD FOR IDENTIFYING A PREDETERMINED NUCLEOTIDE SEQUENCE Bruker Spatial Biology, Inc. (US) 2026-04-29 — — EP disclosed
EP-3794146-B1 METHOD FOR IDENTIFYING A PREDETERMINED NUCLEOTIDE SEQUENCE BRUKER SPATIAL BIOLOGY INC (US) 2025-12-10 — — EP disclosed
US-20250289846-A1 METHODS OF PURIFYING ANTIBODY-NUCLEIC ACID CONJUGATES BRUKER SPATIAL BIOLOGY, INC. 2025-09-18 — — US disclosed
US-20250277263-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2025-09-04 — — US disclosed
CN-112703255-B Chemical compositions and methods of use thereof 布鲁克空间生物学公司 2025-04-29 — — CN disclosed
US-12281356-B2 Chemical compositions and methods of using same BRUKER SPATIAL BIOLOGY, INC. (US) 2025-04-22 — — US disclosed
EP-4514960-A1 METHODS OF PURIFYING ANTIBODY-NUCLEIC ACID CONJUGATES Bruker Spatial Biology, Inc. (US) 2025-03-05 — — EP disclosed
CN-119365595-A Method for purifying antibody-nucleic acid conjugates 布鲁克空间生物学公司 2025-01-24 — — CN disclosed
US-20240279723-A1 COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION BRUKER SPATIAL BIOLOGY, INC. 2024-08-22 — — US disclosed
EP-4168578-B1 COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION BRUKER SPATIAL BIOLOGY INC (US) 2024-08-07 — — EP disclosed
US-20230220461-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2023-07-13 — — US disclosed
CN-116406428-A Compositions and methods for in situ single cell analysis using enzymatic nucleic acid extension 纳米线科技公司 2023-07-07 — — CN disclosed
EP-4168578-A1 COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION Nanostring Technologies, Inc. (US) 2023-04-26 — — EP disclosed
US-11549139-B2 Chemical compositions and methods of using same NANOSTRING TECHNOLOGIES, INC. (US) 2023-01-10 — — US disclosed
WO-2022266416-A1 COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION NANOSTRING TECHNOLOGIES, INC. (US) 2022-12-22 — — WO disclosed
CN-112703255-A Chemical compositions and methods of use thereof 纳米线科技公司 2021-04-23 — — CN disclosed
EP-3794146-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME Nanostring Technologies, Inc. (US) 2021-03-24 — — EP disclosed
US-20190345548-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2019-11-14 — — US disclosed
US-20070060744-A1 Process for the synthesis of pyrazolopyrimidines EPOCH BIOSCIENCES, INC. (US) 2007-03-15 — — US disclosed
US-20070060744-A1 Process for the synthesis of pyrazolopyrimidines EPOCH BIOSCIENCES, INC. (US) 2007-03-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070060744-A1 Process for the synthesis of pyrazolopyrimidines DPYD, PNP, UMPS ADRB1 4570/4885DNMT1 356/4885LMNA 4171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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