Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | PPIA | P62937 | 2/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663227 | 0.85 | PPIA (0.46) | MRGPRX4PPIANPC1RAB9ALTA4H | |
| SCHEMBL7664318 | 0.83 | MRGPRX4 (0.52) | MRGPRX4NPC1RAB9AATRPRKDC | |
| SCHEMBL7714047 | 0.82 | MRGPRX4 (0.51) | MRGPRX4PLAUEGLN1KAT6A | |
| SCHEMBL7662548 | 0.82 | MRGPRX4 (0.51) | MRGPRX4PLAUKMT2AKAT6A | |
| SCHEMBL7660874 | 0.82 | MRGPRX4 (0.47) | MRGPRX4ATRPRKDCPLAUEGLN1 | |
| SCHEMBL6753784 | 0.79 | LOXL2 (0.53) | MRGPRX4PLAUEGLN1KAT6A | |
| SCHEMBL7665912 | 0.79 | MRGPRX4 (0.48) | MRGPRX4NPC1RAB9APLAU | |
| SCHEMBL6751413 | 0.78 | PLAU (0.47) | MRGPRX4PLAUEGLN1KAT6A | |
| SCHEMBL7663246 | 0.78 | MRGPRX4 (0.48) | MRGPRX4PPIAPLAUKMT2AKAT6A | |
| SCHEMBL7658946 | 0.78 | MRGPRX4 (0.51) | MRGPRX4PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348478-B1 | BLOOD COAGULATION FACTORS AND ANTICOAGULANTS | TEIJIN LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| EP-1043311-A1 | BIPHENYLAMIDINE DERIVATIVES | TEIJIN LIMITED (JP) | 2000-10-11 | — | — | EP | disclosed |