Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.55 |
| ▸ | ITGAV | P06756 | 20/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655641 | 0.93 | ITGB3 (0.63) | ITGB3ITGAVITGA2B | |
| SCHEMBL7663330 | 0.75 | ITGB3 (0.62) | ITGB3ITGAVITGA2B | |
| SCHEMBL7659775 | 0.75 | ITGB3 (0.58) | ITGB3ITGAVITGA2B | |
| SCHEMBL7660910 | 0.74 | PLA2G4A (0.43) | — | |
| SCHEMBL7432299 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL7980563 | 0.71 | ITGB3 (1.00) | ITGB3ITGAVITGA2B | |
| SCHEMBL7663435 | 0.70 | ITGAV (0.62) | ITGB3ITGAVITGA2B | |
| SCHEMBL7656181 | 0.70 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL7349374 | 0.70 | ITGB3 (0.70) | ITGB3ITGAVITGA2B | |
| SCHEMBL14271494 | 0.70 | ITGB3 (0.60) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489333-B2 | HETEROCYCLIC COMPOUNDS CONTAINING A GUANIDINE MIMIC, FOR INHIBITION OF CELL ADHESION, TREATMENT OF ANGIOGENESIS DISORDERS, INFLAMMATION, CANCER METASTASIS, DIABETIC RETINOPATHY, THROMBOSIS, RESTENOSIS, MACULAR DEGENERATION | BRISTOL - MEYERS SQUIBB PHARMA COMPANY | 2002-12-03 | — | — | US | disclosed |
| US-20010044535-A1 | Integrin antagonists | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044535-A1 | Integrin antagonists | ITGB3, VCAM1, ITGB2 | ITGB3 1/4885ITGAV 12/4885ITGA2B 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.