SCHEMBL7664679

SCHEMBL7664679

CCc1cccc2c(-c3nc4cc5c(cc4n(OC(C)=O)c3=O)CCC5)cn(CCCN)c12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CAMK2D Q13557 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7659483 0.89 CAMK2D (0.39) CAMK2D
SCHEMBL8368712 0.89 CAMK2D (0.33) CAMK2D
SCHEMBL8366859 0.88 CAMK2D (0.33) CAMK2D
SCHEMBL8368564 0.88 CAMK2D (0.36) CAMK2D
SCHEMBL7665495 0.88 CAMK2D (0.41) CAMK2D
SCHEMBL7656323 0.88 CAMK2D (0.36) CAMK2D
SCHEMBL7664149 0.86 CAMK2D (0.41) CAMK2D
SCHEMBL7663936 0.86 CAMK2D (0.39) CAMK2D
SCHEMBL7657124 0.84 CAMK2D (0.39) CAMK2D
SCHEMBL8365231 0.84 CNR2 (0.37) CAMK2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6458792-B1 MEDICAMENT FOR THE TREATMENT OF INFLAMMATORY, IMMUNOLOGICAL, BRONCHOPULMONARY, CARDIOVASCULAR, ONCOLOGICAL OR CNS-DEGENERATIVE DISORDERS. ASTRAZENECA AB (SE) 2002-10-01 US disclosed
EP-1071683-A1 NEW COMPOUNDS AstraZeneca AB (SE) 2001-01-31 EP disclosed
WO-1999046264-A1 NEW COMPOUNDS ASTRAZENECA AB (SE) 1999-09-16 WO disclosed