Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8368712 | 0.91 | CAMK2D (0.33) | CAMK2DTP53PDE4BPDE4DALDH1A1 | |
| SCHEMBL7659483 | 0.89 | CAMK2D (0.39) | CAMK2DPDE4BPDE4DALDH1A1GSK3B | |
| SCHEMBL8366859 | 0.89 | CAMK2D (0.33) | CAMK2DPDE4BPDE4DALDH1A1GSK3B | |
| SCHEMBL7664679 | 0.88 | CAMK2D (0.32) | CAMK2D | |
| SCHEMBL7656323 | 0.88 | CAMK2D (0.36) | CAMK2DALDH1A1GSK3BPCSK9USP2 | |
| SCHEMBL8365231 | 0.84 | CNR2 (0.37) | CAMK2DMAPTPCSK9 | |
| SCHEMBL8516363 | 0.84 | MAPT (0.36) | PDE4BPDE4DALDH1A1KDM4EMAPT | |
| SCHEMBL8516682 | 0.83 | GSK3B (0.38) | CAMK2DALDH1A1GSK3BUSP2CYP1A2 | |
| Acetic Acid SCHEMBL8368566 | 0.79 | CAMK2D (0.37) | CAMK2DTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL7656438 | 0.77 | CAMK2D (0.42) | CAMK2DGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | claimed |
| WO-1999046260-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 1999-09-16 | — | — | WO | disclosed |