SCHEMBL7664740

SCHEMBL7664740

[C](=Cc1ccccc1)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
G6PC1 P35575 5/20 0.47
TSHR P16473 3/20 0.43
AOC3 Q16853 1/20 0.40
TRPM8 Q7Z2W7 1/20 0.39
LMNA P02545 2/20 0.38
MAOB P27338 2/20 0.38
USP2 O75604 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAOA P21397 1/20 0.38
PYCR1 P32322 1/20 0.38
BLM P54132 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7665169 0.78 NPC1 (0.39) ALDH1A1G6PC1TSHRAOC3LMNA
SCHEMBL7669549 0.75 SIGMAR1 (0.37)
SCHEMBL9128136 0.72 KCNH2 (0.41) LMNA
SCHEMBL3983863 0.70 RELA (0.41) ALDH1A1TSHRLMNAMAOBSMN1; SMN2
SCHEMBL4551293 0.70 ALDH1A1 (0.60) ALDH1A1TSHRAOC3LMNAMAOB
SCHEMBL11107622 0.70 ALDH1A1 (0.60) ALDH1A1TSHRAOC3LMNAMAOB
SCHEMBL26801 0.70 ALDH1A1 (0.60) ALDH1A1TSHRAOC3LMNAMAOB
SCHEMBL1600461 0.70 ALDH1A1 (1.00) ALDH1A1TSHRAOC3LMNAMAOB
SCHEMBL1797079 0.70 ALDH1A1 (0.60) ALDH1A1TSHRAOC3LMNAMAOB
SCHEMBL9126738 0.69 G6PC1 (0.39) ALDH1A1G6PC1TSHRTRPM8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500816-B1 ANTITUMOR NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2002-12-31 US disclosed
EP-1120119-A1 REMEDIES FOR PHOTOCHEMOTHERAPY Nippon Kayaku Kabushiki Kaisha (JP) 2001-08-01 EP disclosed
US-5846730-A Labelled complex CANON KABUSHIKI KAISHA (JP) 1998-12-08 US disclosed
EP-0519474-B1 Labeled complex CANON KK (JP) 1998-09-16 EP disclosed
US-5700647-A LABELED COMPLEX FOR DETECTING SUBJECT COMPOUND TO BE ANALYZED BY OPTICAL MEANS USING NEAR-INFRARED RADIATION COMPRISING SUBSTANCE FROM LIVING ORGANISM AND LABELING AGENT FIXED THERETO CANON KABUSHIKI KAISHA (JP) 1997-12-23 US disclosed
US-5512446-A STORAGE STABILITY CANON KABUSHIKI KAISHA (JP) 1996-04-30 US disclosed
US-5492792-A OPTICAL CARD OR DISKS; EXCELLENT LIGHT SENSITIVITY WITHIN NEAR INFRARED REGION AND HEAT RESISTANCE; STORE INFORMATIONSAT HIGH DENSITY CANON KABUSHIKI KAISHA (JP) 1996-02-20 US disclosed
US-5432770-A Optical recording medium, method of reproducing recorded data of optical recording medium, and system for reproducing recorded data of optical recording medium CANON KABUSHIKI KAISHA (JP) 1995-07-11 US disclosed
EP-0278763-B1 Information recording medium CANON KK (JP) 1995-04-26 EP disclosed
US-5382497-A Optical recording medium and process for recording thereupon CANON KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed
US-5100766-A Subbing Layer Laminate of Polysiloxane and Polysiloxane Substituted with Acrylic Resin, Thermoconductivity CANON KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed
US-5085925-A With thermoplastic bonding layer containing tackifier resin and copolymer of ethylene and acrylic acid or acrylate or terpolymer with maleic anhydride CANON KABUSHIKI KAISHA (JP) 1992-02-04 US disclosed
US-5079128-A Thin film containing a methine dye having at least two dimethylaminophenyl groups and a carbonium ion; laser writing; heat resistance CANON KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
US-5079127-A Methine Dyes CANON KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
US-4944981-A Containing polymethine compound CANON KABUSHIKI KAISHA (JP) 1990-07-31 US disclosed
US-4931337-A CONTAINING ORGANIC MATERIAL, ADHESIVE CANON KABUSHIKI KAISHA (JP) 1990-06-05 US disclosed
US-4923390-A AMINE OR QUATERNARY SALTS USED AS PHOTOSTABILIZERS WITH METHINE DYES; HEAT AND RADIATION RESISTANCE; DURABILITY; OPTICAL CARDS AND DISKS; LASERS CANON KABUSHIKI KAISHA (JP) 1990-05-08 US disclosed
EP-0278763-A2 Information recording medium CANON KABUSHIKI KAISHA (JP) 1988-08-17 EP disclosed
EP-0264274-A2 Optical recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP disclosed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP disclosed