Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665129 | 1.00 | KCNH2 (0.44) | KCNH2TP53NPY5RLMNAPOLB | |
| SCHEMBL7663700 | 0.86 | LMNA (0.48) | KCNH2TP53NPY5RLMNAPOLB | |
| SCHEMBL7663710 | 0.86 | LMNA (0.48) | KCNH2TP53NPY5RLMNAPOLB | |
| SCHEMBL7666705 | 0.85 | NPY5R (0.47) | KCNH2TP53NPY5RLMNABCHE | |
| SCHEMBL7666713 | 0.85 | NPY5R (0.47) | KCNH2TP53NPY5RLMNABCHE | |
| SCHEMBL7672232 | 0.84 | RAB9A (0.49) | KCNH2TP53NPY5RLMNAPOLB | |
| SCHEMBL7672237 | 0.84 | RAB9A (0.49) | KCNH2TP53NPY5RLMNAPOLB | |
| SCHEMBL7669629 | 0.83 | NPY5R (0.48) | TP53NPY5RBCHEACHETRPC3 | |
| SCHEMBL7669635 | 0.83 | NPY5R (0.48) | TP53NPY5RBCHEACHETRPC3 | |
| SCHEMBL7666369 | 0.82 | ADRA1A (0.55) | KCNH2TP53NPY5RBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355641-B1 | HYPOTENSIVE AGENTS AND WOUND HEALING AGENTS | SYNTEX (U.S.A.) LLC | 2002-03-12 | — | — | US | disclosed |