Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815921 | 0.91 | THRB (0.52) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6815074 | 0.79 | THRB (0.65) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6814197 | 0.78 | LMNA (0.66) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7863668 | 0.77 | THRB (0.47) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6810924 | 0.77 | THRB (0.65) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6815056 | 0.76 | LMNA (0.72) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7661565 | 0.75 | THRB (0.60) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6815927 | 0.75 | THRB (0.47) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL6814553 | 0.74 | MAPT (0.77) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7120258 | 0.74 | ALDH1A1 (0.57) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410571-B1 | VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-25 | — | — | US | disclosed |