Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657146 | 0.73 | MEN1 (0.39) | IMPDH2ALDH1A1HPGD | |
| SCHEMBL3594627 | 0.66 | PARP1 (0.32) | ALDH1A1HPGD | |
| SCHEMBL3606933 | 0.65 | PTGS2 (0.31) | — | |
| SCHEMBL3605520 | 0.65 | EZH2 (0.36) | — | |
| SCHEMBL3607869 | 0.65 | PTPN1 (0.38) | PTPN1IMPDH2ALDH1A1HPGD | |
| SCHEMBL1783863 | 0.64 | CA2 (0.39) | PTPN1IMPDH2ALDH1A1HPGD | |
| SCHEMBL17772634 | 0.64 | CA2 (0.39) | PTPN1IMPDH2ALDH1A1HPGD | |
| SCHEMBL3594426 | 0.64 | PTGS2 (0.30) | — | |
| SCHEMBL9070629 | 0.64 | CA2 (0.42) | PTPN1ALDH1A1HPGD | |
| SCHEMBL21468504 | 0.63 | MEP1B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479536-B1 | Benzofuran derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-12 | — | — | US | disclosed |