Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665776 | 0.73 | PTPN1 (0.33) | HPGDALDH1A1IMPDH2 | |
| SCHEMBL2548075 | 0.71 | MAOA (0.38) | MEN1KMT2AMAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7413781 | 0.70 | CA12 (0.43) | MEN1KMT2AMAPTPOLBHPGD | |
| SCHEMBL8802786 | 0.68 | ALDH1A1 (0.38) | MEN1KMT2AHPGDNPSR1ALDH1A1 | |
| SCHEMBL31638876 | 0.68 | CYP3A4 (0.63) | MEN1KMT2AMAPTCYP3A4POLB | |
| SCHEMBL5655590 | 0.67 | CA12 (0.43) | MEN1KMT2AMAPTPOLBHPGD | |
| SCHEMBL7410941 | 0.67 | HTT (0.45) | MEN1KMT2AMAPTCYP3A4POLB | |
| SCHEMBL1817120 | 0.67 | HTR7 (0.31) | — | |
| SCHEMBL2548460 | 0.67 | LMNA (0.43) | MEN1KMT2AMAPTCYP3A4NPSR1 | |
| SCHEMBL7412320 | 0.67 | HTT (0.43) | MEN1KMT2APOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479536-B1 | Benzofuran derivatives, process for the preparation of the same and uses thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-12 | — | — | US | disclosed |