Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS8 | Q16651 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 10/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661082 | 0.91 | CMA1 (0.44) | ELANECTSS | |
| SCHEMBL7665808 | 0.86 | CAPN1 (0.41) | CTSSCYP3A4 | |
| SCHEMBL7660604 | 0.86 | CTSD (0.40) | ELANECYP3A4 | |
| SCHEMBL7661632 | 0.85 | F2 (0.43) | — | |
| SCHEMBL5711290 | 0.85 | PRSS8 (0.49) | PRSS8ELANECTSSCYP3A4CYP2C9 | |
| SCHEMBL7665212 | 0.84 | F2 (0.42) | ELANECYP3A4 | |
| SCHEMBL7661080 | 0.84 | CCR1 (0.46) | ELANECYP3A4 | |
| SCHEMBL7667642 | 0.82 | CMA1 (0.51) | ELANE | |
| SCHEMBL7665870 | 0.80 | CTSD (0.46) | CTSSCYP3A4 | |
| SCHEMBL7669892 | 0.79 | CCR1 (0.47) | ELANECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |