Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | CASR | P41180 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 11/20 | 0.49 |
| ▸ | CNR2 | P34972 | 9/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7382770 | 0.86 | BCAT2 (0.42) | MTNR1AMTNR1BCASR | |
| SCHEMBL7391823 | 0.81 | CACNA1B (0.52) | EPHX2MEN1KMT2A | |
| SCHEMBL17152620 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BEPHX2MEN1KMT2A | |
| SCHEMBL17152612 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2A | |
| SCHEMBL7391206 | 0.79 | LMNA (0.48) | MEN1KMT2A | |
| SCHEMBL17152384 | 0.75 | SMN1; SMN2 (0.43) | EPHX2KMT2A | |
| SCHEMBL5184559 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2A | |
| SCHEMBL4952911 | 0.75 | ALDH1A1 (0.46) | MEN1KMT2A | |
| SCHEMBL3642993 | 0.74 | MTNR1A (0.68) | MTNR1AMTNR1BCASRCNR1CNR2 | |
| SCHEMBL17152413 | 0.74 | MTNR1A (0.56) | MTNR1AMTNR1BCNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | disclosed |