SCHEMBL7666109

SCHEMBL7666109

CC(CC(=O)OC1CCCCC1)NC(=O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
SCN1A P35498 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47
RAB9A P51151 4/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47
CTSL P07711 2/20 0.45
CTSB P07858 1/20 0.45
CTSS P25774 1/20 0.45
CTSK P43235 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
HTT P42858 1/20 0.44
CACNA1B Q00975 1/20 0.42
NPC1 O15118 2/20 0.42
F10 P00742 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7671932 0.89 SMN1; SMN2 (0.48) CYP1A2RAB9AALDH1A1HPGDCTSL
SCHEMBL28279331 0.80 PREP (0.48) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL1185757 0.79 RAB9A (0.58) LMNARAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL28544688 0.78 LMNA (0.64) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL7671894 0.78 SMN1; SMN2 (0.47) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL7663015 0.77 CTSL (0.50) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL7883090 0.77 ALDH1A1 (0.55) LMNARAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL8972788 0.76 RAB9A (0.55) LMNARAB9AALDH1A1HPGDSMN1; SMN2
SCHEMBL5348991 0.76 CACNA1B (0.70) RAB9AALDH1A1CTSLCTSSCACNA1B
SCHEMBL8972504 0.75 RAB9A (0.57) LMNARAB9AALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6348614-B1 PROTECTING CROPS AGAINST PLANT DISEASES AGROGENE LTD. (IL) 2002-02-19 US claimed
EP-0948481-A1 AMINOBUTYRIC ACID FUNGICIDES Agrogene Ltd. (IL) 1999-10-13 EP claimed
WO-1998029387-A1 AMINOBUTYRIC ACID FUNGICIDES AGROGENE LTD. (IL) 1998-07-09 WO claimed
US-6348614-B1 PROTECTING CROPS AGAINST PLANT DISEASES AGROGENE LTD. (IL) 2002-02-19 US disclosed
EP-0948481-A1 AMINOBUTYRIC ACID FUNGICIDES Agrogene Ltd. (IL) 1999-10-13 EP disclosed
WO-1998029387-A1 AMINOBUTYRIC ACID FUNGICIDES AGROGENE LTD. (IL) 1998-07-09 WO disclosed