Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL955395 | 0.85 | SMN1; SMN2 (0.40) | KMT2AUSP2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL31542129 | 0.84 | CYP2B6 (0.58) | KMT2AUSP2NOTUMALDH1A1MAPK1 | |
| SCHEMBL7666262 | 0.82 | SMN1; SMN2 (0.41) | KMT2AUSP2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL17523153 | 0.81 | BLM (0.59) | KMT2AALDH1A1NPC1RAB9ACKS1B | |
| SCHEMBL9650536 | 0.80 | CYP2B6 (0.46) | ALDH1A1MAPK1CYP2D6SMN1; SMN2 | |
| SCHEMBL818967 | 0.79 | CHRM1 (0.47) | KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL27906266 | 0.79 | TSHR (0.57) | KMT2AALDH1A1CYP2C19NPC1RAB9A | |
| SCHEMBL2867370 | 0.79 | GPR119 (0.53) | KMT2AUSP2ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL22106794 | 0.78 | MEN1 (0.42) | KMT2AALDH1A1NPC1 | |
| SCHEMBL17523154 | 0.77 | MGLL (0.56) | KMT2AUSP2ALDH1A1MAPK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355640-B1 | TREATMENT OF HYPERTENSION, UROGENITAL DISORDERS AND FORMED BY WITTIG REACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |
| US-5773530-A | USEFUL AS PSYCHOSTIMULANTS, ANTIHYPERTENSIVE AGENTS AND REMEDIES FOR RENAL FAILURE, DIURETICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |